RAD21 encodes a protein involved in DNA double-strand-break repair54, shows high-level amplifications in 37% of the TCGA breast cancer cases, and presents a significant transcriptional correlation with SQLE GE (ρ = 0.62) (data from http://www.cbioportal.org, accessed May 2nd, 2015). The gene discussed is RAD21; the disease is breast carcinoma.