CARD11 and diffuse large B-cell lymphoma: It has been reported previously that CK1α binds to CARMA1 and regulates the CBM complex in activated T cells and ABC DLBCL.21 However, the recruitment of other WNT signaling components was unexpected and we therefore verified the interaction to CARMA1 L225LI by reciprocal IP of endogenous CK1α, β-catenin and GSK3β (Figure 3a).