Increasing evidence points to deregulation of protein synthesis downstream of mTOR, at the level of EIF4EBP1, as playing a central role in tumor formation.39 EIF4EBP1 is capable of mediating the oncogenic effects of AKT signaling on mRNA translation, cell growth and tumor progression.40 In this study, we found that overexpression of EMC6 reduces levels of p-EIF4EBP1, while EMC6 knockdown elevates p-EIF4EBP1 levels. Here, EMC6 is linked to neoplasm.