MCL1 and glioblastoma: Ku70, a component of the non-homologs end joining DNA repair pathway, was recently shown to interact with and deubiquitylate Mcl-1, thereby linking DNA repair to apoptosis.23 Whether the activity of Mcl-1-specific ubiquitin ligases is increased or the Ku70 deubiquitylating activity is reduced after IR in apoptosis-inducing glioblastoma cells, this needs further investigation.