Thus, both IL-23 and IL-17 form a new axis through Th17 cells, which play an important role in many autoimmunity and chronic inflammation diseases, such as experimental autoimmune encephalomyelitis, rheumatoid arthritis, and inflammatory bowel disease [28–30], and targeting on them has become a new strategy for these kind of diseases as some exciting news have been reported in several articles [31, 32]. This evidence concerns the gene IL23A and Autoimmunity.