IL1B and uveitis: Although uveitis specialists use a number of standard immunosuppressants off-label (e.g. methotrexate, mycophenolate, etc.), animal models of uveitis and in vitro human data are enabling the identification of specific pathways that may be targeted in uveitis, including the role of interleukin-17 (IL-17) secreting T- helper cells (Th17), and the pro-inflammatory cytokines IL-6 and IL-1β.