TET2 and chronic myelomonocytic leukemia: TET2 (ten-eleven translocation (TET) oncogene family member 2) is a member of the TET family of proteins.22 Although TET2 mutations are widely prevalent in CMML, thus far, they have not been shown to independently impact either OS or LFS.1 In the current study, TET2 mutations were seen in 46% of CMML patients and the absence of TET2 mutations negatively impacted OS.