A sub analysis was carried out based on HIV status which showed that MTB specific to mitogen specific IP-10 ratio was significantly higher in the HIV negative active TB cases, 3.85 (1.57–6.82) compared to the HIV negative latently infected contacts, 1.62 (1.36–2.62), p = 0.0004 (Fig 1D). Here, CXCL10 is linked to tuberculosis.