CDH1 and cancer: It is widely accepted that EZH2 overexpression is correlated with aggressiveness and invasive capacity in various types of cancers (see [103] for review) and it has been implicated in repressing the expression of E-Cadherin in nasopharyngeal cancer [104], renal cell carcinoma [105], oral tongue squamous carcinoma [106], and prostate and breast cancers [107].