IGKV4-1 and neoplasm: Integrin β3-deficiency had no effect on the collagen fibril diameter in dermis when comparing β3-KO mice (68.0 ± 11.7 nm, n = 5 mice) with WT mice (73.8 ± 6.8 nm, n = 4 mice) (Figure 7E,F), indicating that the lack of stromal β3 integrin can specifically influence tumor fibrosis.