CCL2 and open-angle glaucoma: Because the level of aqueous MCP-1 was related to the surgical success of trabeculectomy in open-angle glaucoma and postoperative modulation of filtering route created by trabeculectomy for aqueous humor [23], [24], the constitutive high levels of inflammatory cytokines in aqueous humor may affect the scaring process of filtering bleb after trabeculectomy in UG similarly.