TNFSF10 and malignant colon neoplasm: In this work, we show for the first time that HT29 human colon cancer cells co-treated with TRAIL and a supernatant of propionibacteria, or a mixture of propionate and acetate (C3/C2), displayed quite similar transcription modulation pattern, with changes in expression of genes involved in apoptosis, suggesting a potential synergistic pro-apoptotic effect of these combinations.