A study evaluating dietetic modulation (with reduced caloric and saturated fat intake) as exclusive form of treatment for NAFLD in 31 subjects showed that, after 6 months, those who were considered adherent to the protocol (loss ≥ 5% of baseline weight) had lower BMI, waist circumference, ALT and GGT levels, visceral fat and hepatic density (analyzed by computed tomography), and HOMA-IR index (Homeostasis Model Assessment-Insulin Resistance). This evidence concerns the gene GPT and Insulin resistance.