Therefore, the aim of the present study was to investigate the association between the haemostatic biomarkers VWF, ADAMTS13, and D-Dimer, the proinflammatory cytokines INF-γ, IL-6, and TNF-α, and the anti-inflammatory cytokine IL-10 with CKD in DM1 patients. This evidence concerns the gene VWF and chronic kidney disease.