In general, inflammatory and haemostatic biomarkers were significant associated with CKD, corresponding to OR of 1.021 (1.008–1.035) for INF-γ, 1.006 (1.002–1.011) for TNF-α, 1.224 (1.051–1.426) for IL-6, 1.002 (1.000–1.003) for IL-10, 1.003 (1.001–1.004) for VWF, 1.005 (1.002–1.007) for ADAMTS13 antigen, 1.030 (1.009–1.051) for ADAMTS13 activity, 0.667 (0.490–0.907) for VWF/ADAMTS13 antigen, 1.129 (1.031–1.236) for VWF/ADAMTS13 activity, 7 × 10−11 (4 × 10−15–1 × 10−5) for ADAMTS13 activity/antigen, and 1.008 (1.004–1.012) for D-Dimer. This evidence concerns the gene ADAMTS13 and chronic kidney disease.