Inflammatory markers, such as C-reactive protein (CRP), tumor necrosis factor (TNF), interleukin-6 (IL-6), interleukin-18 (IL-18), monocyte chemotactic protein-1 (MCP-1), and acute phase serum amyloid A (APSAA), increased in women with PCOS compared with the normal [98–102]. This evidence concerns the gene CRP and polycystic ovary syndrome.