GATA3 and cancer: We also demonstrated that patients with GATA3-positive muscle-invasive tumor had a significantly higher risk of disease progression in a univariate setting (P = 0.048) and, in this subgroup, strong GATA3 expression was correlated with tumor progression (HR = 2.435; P = 0.052) or cancer-specific survival (HR = 3.673; P = 0.040) in a multivariate setting [117].