Irrespective of this, both immunohistochemical and molecular analyses detecting hepatic RFP expression showed that similar numbers of CT26‐RFP cells reached the liver of Tie2‐GFP and Tie2‐IFNα mice by 5 min post‐injection (Fig 3B [top panels] and C, and Appendix Fig S3A), indicating that the higher IFNα levels detected in Tie2‐IFNα mice did not affect the capacity of CRC cells to initially engraft the liver parenchyma. The gene discussed is TEK; the disease is colorectal carcinoma.