ANGPT2 and colorectal carcinoma: In fact, 7 days after CRC cell injection, the metastatic foci in Tie2‐GFP mice were highly proliferative (as denoted by positivity to the Ki67 signal, Fig EV4A) and associated with newly formed vessels (as denoted by positivity to the CD34 signal, Fig EV4B) and with the significant upregulation of the pro‐angiogenic marker Angpt2 (Appendix Fig S3B).