Of note, Tie2‐IFNα mice showed a 70% reduction in the appearance of peritoneal carcinomatosis at both days 21 and 28 post‐transplant (a complication of Glisson's capsule infiltration, with CRC cells spreading into the peritoneal cavity) when compared to Tie2‐GFP mice (Fig 5C and D, and Movie EV8). Here, IFNA1 is linked to colorectal carcinoma.