By days 25 and 35 post‐CRC cell injection—time points at which liver lesions are macroscopically and microscopically evident (Fig 1C)—the number of hepatic TEMs detected by flow cytometry increased (Fig 1B), and this occurred concomitantly with a commensurate increase in hepatic Tie2‐driven GFP mRNA expression (Fig 1D). Here, TEK is linked to colorectal carcinoma.