Follow‐up MRI analyses at days 21 and 28 post‐transplant revealed similar numbers of intrahepatic lesions (average metastasis number at days 21‐28: Tie2‐GFP = 3 ± 0.53; Tie2‐IFNα = 3.12 ± 0.63); however, Tie2‐IFNα mice displayed reduced volumes of CRC liver metastases when compared to those detected in Tie2‐GFP mice (Fig 5B and C, and Movie EV8). The gene discussed is IFNA1; the disease is colorectal carcinoma.