KAT2B and triple-A syndrome: In order to determine the acetylation of the main histone substrates of KAT2B, KAT3B, and KAT6B (Additional file 1: Table S2) [8], expression of H3K9ac, H3K14ac, and H3K18ac was determined in AAA tissue samples compared with healthy aortic tissue specimens by Western blotting.