UBC and leukemia: To further assess the requirement of Prmt1 for leukemia maintenance, we transduced MOZ-TIF2 leukemic cells carrying a ubiquitin C promoter (UbC)-driven luciferase reporter (Becker et al., 2006) harvested from primary leukemia mice with either shPrmt1 or scramble control lentivirus prior to transplantation into syngeneic mice for leukemia development.