High serum triglyceride levels can results from frequent heparin use and elevated parathyroid hormone.35 In uremia patients, hypertriglyceridemia can also result from a relative increase in plasma ApoC3 (an inhibitor of lipoprotein lipase) and a relative decrease in plasma ApoC2 (an activator of lipoprotein lipase).8 Our immunoblotting results showed that ApoC3 levels were higher in L5 from HD patients than in any other LDL subfraction. The gene discussed is APOC3; the disease is uremia.