In fact, in a recent cohort of 112 septic patients, the ability to predict AKI within 24 h was fair using plasma cystatin C [AUC 0.737 (95 % CI 0.633–0.841)] and good using plasma NGAL [AUC 0.830 (95 % CI 0.741–0.919)] [25]. The gene discussed is CST3; the disease is acute kidney injury.