Of note, miR-548c-regulated genes can potentially modulate numerous well-known pathways associated with tumor growth and metastasis, including pathways in cancer, mTOR pathway, adherens junction, cell cycle, acute myeloid leukemia, pancreatic cancer, notch signaling pathway and jak-stat signaling pathway (Fig. 3a), indicating the possibility that miR-548c has broad influence over diverse oncogenic pathways. This evidence concerns the gene MTOR and familial pancreatic carcinoma.