We then analyzed LCL RNA from patient P842CT.1 (heterozygous for MLH1 c.842C>T) by comparing to those from 5 controls, including: 3 healthy individuals, and 2 Lynch syndrome patients (P791-5TG.1 and P882CT.1) carrying MLH1 c.791-5T>G and c.882C>T mutations directly altering the 3’ss or 5’ss of exon 10, respectively [36]. Here, MLH1 is linked to Lynch syndrome.