IGHE and asthma: The model of experimental asthma with duration of 30 days, based on SC sensitization with 50mcg of Der p with aluminum hydroxide, in three applications, followed by a daily nasal challenge with Der p 50mcg in 10mcL of saline for 7 days, and euthanasia 24 hours after the last challenge, was effective in the development of specific IgE and IgG1, eosinophilia in the peribronchovascular space, and airway remodeling.