Although not included inthe AAN recommendations, studies indicate that S-100β protein may be superior toNSE for determining the prognosis after cardiac arrest.(32) However, its value is less well documented and morecontroversial than NSE.(68) Thisbiomarker has not been evaluated because it was not available in our laboratory when thestudy was designed, but it may have an important role in determining neurologicaloutcomes. Here, ENO2 is linked to cardiac arrest.