NPPB and hydrops fetalis: In the case-control study Muerte Subita enInsuficiencia Cardiaca (MUSIC), elevation of ST2 and NT-proBNP above the cut-offvalue was associated with a high rate of sudden death (71%), in contrast with avery low rate (4%) when the two biomarkers were below the threshold (Figure 5).32 This is an important pieceof information considering that, at present, no single test reliably predictssudden death in patients with HF.