LGALS3 and heart failure: First, we dividedthe patients in two groups on the basis EF, reduced or preserved (< 40% or≥ 40%, respectively) (Table 1).Median serum levels of galectin-3 were not significantly different (p = 0.9)between patients with heart failure with reduced EF (8.2 ng/ml [3.6-14.0])(median and IQR) and those with heart failure with preserved EF (9.7 ng/ml[3.7-12.0]).