KDM8 and hepatocellular carcinoma: To further explore the effect of JMJD5 on HCC cell proliferation, we transiently transfected the recombinant plasmid pcDNA3.1B, which encodes JMJD5, into MHCC-97H, HuH-7, HCC-LM6 and L02; as a negative control, a plasmid containing the reverse JMJD5 sequence was used.