By analyzing TCGA data we surprisingly found that the lower expression of JMJD5 was significantly correlated with age (≤ 60 or > 60 year old, P = 0.0082), tumor stages (P < 0.05), overall survival (≤ 24 or > 24 months, P = 0.0222) and overall survival status (dead or alive, P = 0.034) (Table 1). The gene discussed is KDM8; the disease is neoplasm.