Among identified piRNAs, Hsa_piR_017723_DQ594464 putatively targets FOS, a positive modulator of myeloid differentiation of hematopoietic progenitor [49]; hsa_piR_020814_DQ598650 targets SOX4, an apoptosis regulator in different human cancers [50, 51]. The gene discussed is SOX4; the disease is cancer.