Compared to white (W) women, black (B) women with breast cancer are more likely to be younger at diagnosis (Clarke et al. 2003), carry hormone receptor (HR)-negative breast cancer (Iqbal et al. 2015), present with more advanced stage at diagnosis (Kurian et al. 2010), and have higher rates of BRCA1/2 mutations or polymorphisms (John et al. 2007; Nanda et al. 2005). The gene discussed is BRCA1; the disease is breast cancer.