Multivariate Cox regression analysis enrolling the abovementioned significant parameters revealed that BANCR expression (relative risk [RR] 4.245; P = 0.015), tumor size (RR 2.655; P = 0.039), venous infiltration (RR 3.278; P = 0.022), and TNM stage (RR 6.379; P = 0.006) were independent prognostic markers for overall survival of HCC patients (Table 2). This evidence concerns the gene BANCR and hepatocellular carcinoma.