PROM1 and hepatocellular carcinoma: The cell growth rate was determined by a CCK-8 assay, and results showed that HCC cell lines with a high percentage of CD133+ cells (Huh7 and PLC8024) were more resistant to rhIFN-γ treatment than were HCC cell lines with a low percentage of CD133+ cells (BEL7402 and QGY7701) (Fig. 2b).