The results indicated that serum concentration of AFP in liver trauma patients less than 40 ng/ml, and (84.0 ± 27.0) ng/ml in non‐metastasis HCC patients, (374.0 ± 145.9) ng/ml in intrahepatic or nidus metastasis HCC patients and (506.6 ± 89.4) ng/ml in lung metastasis HCC patients. Here, AFP is linked to hepatocellular carcinoma.