Although not investigated in a context of obesity, a previous study demonstrated that the homing of ovarian cancer cells to the omentum (a large fat pad that extends from the stomach and covers the bowel and the most frequent intra-peritoneal localization of metastatic ovarian cancer) might predominantly involve a CXCR1/CXCL8 axis, at least in vitro and in murine models46. Here, CXCL8 is linked to obesity due to melanocortin 4 receptor deficiency.