BCR and Familial prostate cancer: As shown in Table 1 and Fig. 4b, CCR3 expression was positively correlated with Gleason score, the size of the undifferentiated component (percentage of tumour classified as Gleason 4 or 5), localization at the peripheral zone of the prostate gland, local extension of the prostate cancer (shown by pT stage), the presence of lymphatic emboli and biochemical recurrence (BCR).