HuH-7 is a selected HCC cell line with more mesenchymal characteristics compared to HepG2 cell line; indeed, it has been previously showed that HuH-7 cells express mesenchymal markers (Vimentin and Zeb1) contrarily to HepG2 cells, which mainly express epithelial markers (E-cadherin and ErbB3) [8]. The gene discussed is ERBB3; the disease is hepatocellular carcinoma.