Consistent with previous results [27], GLI1 and GLI3 (HH pathway transcriptional effectors), PTCH1 (HH signaling repressor and target gene), SMO (HH signaling activator), IHH and SHH (HH pathway ligands) were expressed in ovarian tumors, albeit at variable levels (Figure 1B). This evidence concerns the gene SMO and ovarian neoplasm.