XIST and cancer: There was a very high-degree of commonality across all the models, with three Y-chromosome genes selected across all 17 cancers (ZFY, EIF1AY, and DDX3Y), RPS4Y1 (also on the Y-chromosome) selected across 15 of 17 cancers, and XIST (on the X-chromosome) selected across 14 of 17 cancers.