Notably, the analysis of the expression of several major components of SOCE revealed that SOCE deficiency in the cells from idPD patients was not associated with reduction in Orai1, TRPC1, STIM1 or STIM2 expression: Fig. 1f and Supplementary Figs 3 and 4 demonstrate no difference in mRNA levels for these genes in control and PD patients. This evidence concerns the gene STIM2 and Parkinson disease.