Several single nucleotide polymorphisms (SNPs) have been found in the AdipoQ, including the rs3774261, rs1063537 and rs2082940, and many of these SNPs have been associated with various disease conditions such as CHD, diabetes, hypertension, obesity, rheumatoid arthritis, myocardial infarction, and many more [24–40]. This evidence concerns the gene ADIPOQ and obesity due to melanocortin 4 receptor deficiency.