Six common human pancreatic cancer cell lines (Capan-1, SW1990, COLO357, BxPC-3, MiaPaCa-2, and PANC-1) and one human pancreatic duct epithelial cell line (HPDE) were selected and used to determine the protein and mRNA expression of mutant p53, cavin-1, and caveolin-1 by western blot and qRT-PCR, respectively. Here, CAV1 is linked to familial pancreatic carcinoma.