EIF2AK3 and hepatocellular carcinoma: Western blot analysis (Fig. 1b and Additional file 3: Figure S2) and immunostaining (Fig. 1e) showed that the Perk-mediated phosphorylation of eIf2α was reduced in the HCC tissues of aPlGF-treated and PlGFKO mice compared to IgG-treated and wild type controls resp..