In the Eμ-driven mouse model Romesser et al found differential expression of ENO1, CALR, CFL1 and PPIA by comparing the proteome of activated B cells to B cell lymphoma[11] Consistent with their results we found downregulation of CALR and upregulation of the modified CFL1 protein and PPIA in lymphoma compared to LCL cells. Here, CALR is linked to B-cell non-Hodgkin lymphoma.