DNAJB8 and hereditary clear cell renal cell carcinoma: In a previous study, we found that DNAJB8 is expressed in CSCs/CICs derived from mouse and human renal cell carcinoma (RCC) line cells RenCa and ACHN, and we found by using siRNA technology that DNAJB8 has a role in the maintenance of RCC CSCs/CICs [10].