In the APAC patients, the levels of G-CSF (P = 0.001), IL-6 (P = 0.000), IL-8 (P = 0.000), MCP-1 (P = 0.000), MCP-3 (P = 0.008), MDC (P = 0.009), MIP-1β (P = 0.001), and VEGF (P = 0.035) in AH samples from unilateral APAC affected eyes were significantly higher than those from fellow eyes with PACS (Fig. 1). This evidence concerns the gene CCL4 and aldosterone-producing adrenal cortex adenoma.