The increased expression of FUT8 and the extent of core fucosylation are reported to be altered under pathological conditions such as hepatocellular carcinoma and liver cirrhosis (Miyoshi et al. 1999; Noda et al. 2003; Bernardi et al. 2013), and is strongly linked to age-related changes in glycosylation in the liver (Vanhooren et al. 2007, 2010). Here, FUT8 is linked to hepatocellular carcinoma.