An 80-kDa PEDF receptor (PEDF-RN) with high affinity to the 44-mer PEDF peptide, is involved in neurotrophic activity, and a 60-kDa PEDF receptor (PEDF-RA) with high affinity to the 34-mer PEDF detected in plasma membranes of retina, retinoblastoma, and central nervous system [15, 36, 47–49]. Here, SERPINF1 is linked to retinoblastoma.