To determine if TXA2 analog-induced IUGR would affect the intestine barrier integrity and inflammatory function of the developing mouse pups, we measured gene expression of two key intestinal tight junctional proteins, ZO-1 and occludin, as well as several cytokines involved in intestinal inflammation including IL-1β, IL-6, IL-8, and TNF. The gene discussed is IL6; the disease is fetal growth restriction.