CD8A and infection: By loading naïve and memory TB10Rg3 CD8+ T cells with eFluor450, we determined that both memory and naïve TB10Rg3 CD8+ T cells begin to proliferate and downregulate CD62L first in the MLN by d11 post-infection (Fig 4D), during which time they maintain their 1:1 ratio despite significant proliferation (see below).