In serous ovarian cancer, the ERBB4 CYT-1 variant we expressed in Ba/F3 cells was identified as independent prognostic factor for survival [60], and may cooperate with NRG1 autocrine signaling to support ERBB3-mediated ovarian cancer cell proliferation in vivo [61]. The gene discussed is ERBB3; the disease is ovarian serous adenocarcinoma.