GBP7 and malaria: When a test for general population differentiation, that is, irrespective of malaria, was applied using the XTX statistic described by Gunther and Coop (2013), significant (P < 0.05) signals were found for SNPs rs1128127 in the DERL3 gene and rs84833095 in the TLR1 gene, and marginally significant signals (P < 0.10) were found for SNPs rs2706384 in the IRF1 gene and rs1803632 in the GBP7 gene (supplementary fig.